Melatonin may be effective for migraine headaches prevention. Compared to a placebo, a 3 milligram dose of Melatonin reduced the number of headache days in migraine patients. According to research results presented at the 2013 International Headache Conference, 178 patients were recruited for a trial. The trial compared 3 mg Melatonin, Amitryptylline (antidepressant), and placebo […]

Vitamin B12 deficiency may increase the risk of stroke by increasing the levels of Homocysteine. High Homocysteine level may cause early artheriosclerotic changes within vessels’ wall (hardening of vessels). By lowering Homocysteine level with vitamin B supplementation (vitamin B12 and folic acid) one may be able to reduce the risk of stroke. Blood testing may […]

Approximately 50% of patients with narcolepsy remain undiagnosed. Typically, these patients complain about “being tired all the time.” You may benefit from seeing a board certified sleep specialist. Being tired of fatigued all the time may not necessarily be a sign of being “overworked” or having a depression. The reason may be narcolepsy. To identify […]

Clinically, patients often report that changes in sleep can bring on migraine headaches. One study found there was first human migraine gene linked to enzyme involved. Patients report that altering sleep pattern increases their migraine headaches. There is also a link between sleep pattern and the most severe vascular headaches such as cluster headaches, in […]

Lower melatonin concentrations were found in a night-shift workers, people who were exposed to artificial light at night. It was found that this increases the risk for diabetes as well. The risk increases with number of years of shift work performed. Insufficient sleep is also risk factor for weight gain and obesity.

There is some data that women with the lowest secretion of melatonin had about twice the risk of developing type 2 diabetes (after controlling for demographic lifestyle and other risk factors). It was concluded than more research is needed to elucidate final association between sleep melatonin concentration and type 2 diabetes. It is still not […]

The sleep hormone, melatonin which is a key regulator of sleep could be also important link collecting circadian timing and insulin secretion. Melatonin production is suppressed by light and peaks around 3 to 5 hours after sleep onset. It regulates the sleep-wake cycle by lowering body temperature and causing drowsiness and promoting sleep. It was […]

There is strong evidence (Lancet, June 2013) that insufficient sleep and disruption in circadian rhythm contribute to pathogenesis of metabolic disorders, cardiovascular disease, and cancer. Since world wide metabolic syndrome is on the rise, epidemiological and clinical studies have shown that short duration and poor quality of sleep may predict the development of type 2 […]

In a recent analysis of data from epidemiological studies, investigators found that individuals with obstructive sleep apnea and disturbed sleep secondary to that had developed dementia. One hundred patients had been followed for over a decade and two multi- longitudinal studies trying to determine cardiovascular risk factors of sleep apnea. The results were adjusted for […]

  A. Narcolepsy 35-years old woman presented for years with episodes of un-specific dizzy spells, headaches, almost black out spells when tired. Her husband describes spells of drunkenness followed by headaches and the need for sleep. She was seen by few neurologists, had numerous tests (including MRI of brain, EEG, EKG, Holter, and Echo). Within […]